Historically, CBZ has been the drug of choice in the United Kingdom, but MMI has been the drug of choice in all other areas of the world. My endo is suggesting that in an years time I try coming off again, but I suffer badly with my eyes and have had no trouble on the carbimazole so am very reluctant. There are some frightening dilemmas involved in having this condition, that's for sure. I have been on 5mgs of carbimazole for 2years. They use it as an indicator to see how active the autoimmune disease still is. I had graves desease I was in remission for 15 years it came back I was on carbinmazole anyway nearly 12 months I had my hospital appointment Wednesday I was on 10 mg of carbinmazole in the mornings I was told to stop taking it completely as I'd been stable since march 'I've got to have a blood test in 5 weeks and to return too the hospital in 6 weeks does anyone no us normal for them to just stop carbinmazole from 10mg to nothing. If necessary, have the test done privately. Google was no help . Like you I don't know if I have Graves or not because I wasn't tested but I do have a lot of trouble with gritty, dry eyes and I can't wear my contacts for very long now. My endo decided to give it a try (remission) after one year and since then I have been in remission (almost 2 years now). We prospectively investigated the effects of rate of carbamazepine (CBZ) withdrawal and CBZ level on seizure type and frequency in 12 epilepsy patients withdrawn completely from antiepileptic drugs prior to entering an investigational monotherapy trial. My doctor is … Seems that conversion is nearly complete. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. Results: In the first case symptoms were distressing and subsided with withdrawal of the drug. Any thyroid conditions make life a roller-coaster experience but this site is so helpful and it reminds us that we are not alone (although I wouldn't ever tell the Endo this!). A white blood cell count should be performed if there is any clinical evidence of infection. Thanks, Duster. "i am taking 10mg of carbimazole daily for my hyperthyroism condition. 1 The other patient developed unilateral deafness, tinnitus, and polyarthritis 10 months after starting propylthiouracil, the tinnitus persisting after complete recovery of hearing. Your endo should test you for that. Hi 2 Both these patients were acutely unwell and had … Is methimazole similar medication to Carbimazole for hyperactive thyroid? can manage as i am controling my food intake high in colestrol. I am trying to come off carbimazole after almost 2 years to see if I'm in remission but every time I come off or even cut down, I get symptoms of agitation, faster heart rate, odd sensations in my head. Propylthiouracil can be used instead if you develop a side-effect to carbimazole, or it may be used in a thyrotoxic crisis. I know soy and cruciferous vegetables are on that list. I understand from a book by Mary Schomon (Living Well with Graves' Disease) that the test is actually reliable enough. Hiya I have just been diganosed with overactive thyroid and been given carbimazole just wondered if anyone else has been on this i was given it on Tues but still haven't started it yet think i scared myself half to death by looking on internet about this drug,, i have been back to gp and spoke to him about it just be nice to talk to anyone else who is on this. I have graves for over 4 years now and taking carbimazole long term. Any health question asked on this site will be visible to the people who browse this site. I wonder if anyone with hyper can offer help or advice? Yes I thought that might be the case Linanne. Arrange emergency admission if there are symptoms suggesting a serious complication, ... as a dose reduction or drug withdrawal of antithyroid medication may be needed. I read somewhere that the goiter size is an indicator for the chance of remission: the smaller the goiter, the higher the chance for remission. Use of this site is subject to our Terms & Conditions, Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties. Well you need to continue it. He was started on oral prednisolone 50 mg per day and carbimazole was continued. The most common minor reactions are nausea, headache, arthralgia, mild gastrointestinal disturbance, skin rashes and pruritus. Do regular work out and diet control hold the key . Neutropenia and agranulocytosis Manufacturer advises of the importance of recognising bone marrow suppression induced by carbimazole and the need to stop treatment promptly. This is my second time on carbimazole, my first was about four months after the birth of my son, i had the racing heart and heat intolerance and other symptoms but mostly of underactive thyroid and i too gain two, three stone. My doctor has just stopped my carbimazole to see how ... would be safer staying on the carbimazole for now. The FT4 level is persistently raised six months after completion of radioactive iodine treatment, as this may indicate suboptimal treatment. just started propranolol 10mg two tablets twice a day and carbimazole 5mg three tablets twice ..... should I take the next dose? However, if your blood shows you're hyper again, then it's a different story of course. Hope everything goes well for you. Give the medicine at least 6 weeks to work. The most common adverse effects associated with carbimazole administration are gastrointestinal signs (Bucknell, 2000). I had indeed a very small goiter while sick, so in my case it applies. I was told I needed to have RAI or surgery but I keep refusing as neither is what I want. My periods were back to 28 day cycle since July 2011. thank you ...hello....i have been diagnosed to have a hyperthyroidism and currently Im on carbimazole ... View answer, I have been overactive since May last year ,was put on carbimazole35m. MD. xxx. Answered by Dr. Bhavin Patel: Stopping may cause: Stopping the medication may worsen your symptoms. But of course doctors can't actually say for sure why someone gets the disease, which is highly dissatisfactory. Feel like I'm going insane What else can I do ... View answer, t4 was 27 at time of treatment starting. Thank you for any light you might be able to shed on this. I am a little anxious about it, as 5 years is a long time to be on medication, but am ready to give it a go. While we cannot always control the stress in our lives (I moved country 3 times and lost my father in the last couple of years), I do try to manage it regarding my work and other factors that I know stress me out a bit (I'm an introvert, so too much social interaction makes me unhappy). "i am taking 10mg of carbimazole daily for my hyperthyroism condition. I also have met with indifference, also dogma and a degree of bullying. ... View answer, Dermal ip balm but seems to be having less effect of late . xx. I hope you get it sorted soon. The study was approved by the Hospital … When your thyroid gland produces too much thyroid hormone, it can cause many of your body's functions to speed up, and this leads to symptoms such as losing weight, sweating, feeling irritable or shaky, and diarrhoea. Carbimazole during pregnancy and lactation Carbimazole can be used in pregnancy. I think your body needs to find its balance again. Serial thyroid function monitoring is recommended, together with appropriate dosage modification in order to maintain a euthyroid state. Answered by Dr. Bhavin Patel: Stopping may cause: Stopping the medication may worsen your symptoms. Relapse after carbimazole withdrawal was defined as recurrence or persistence of abnormal thyroid hormones requiring further treatment. After 5 years I'm about to stop all medication, to see if I go hyper again or not. In the carbimazole-T4 group, the dose of carbimazole was not changed, but 100 micrograms of T4 per day was added to the regimen and the dose was adjusted to maintain an undetectable serum thyrotropin concentration (< 0.04 microU per milliliter). Very likely your dose of Carbimazole should be reduced, possibly substantially. It is a carbamate ester and a member of 1,3-dihydroimidazole-2-thiones. It is very important to know if your hyperthyroidism is caused by an autoimmune disease. A prodrug for methimazol, carbimazole is used for the treatment of hyperthyroidism.It has a role as a prodrug and an antithyroid drug. will i gain weight from the medication and what will happen if i stop taking?" Thank you for this, Misky - it's encouraging on many levels. These are symptoms of hyperthyroid/graves. Other adverse effects that have been reported include excoriations of the head and neck, lymphadenopathy, pruritus, lymphocytosis, and leucopenia (Mooney et al, 1992). I would advise you to determine the stress factors in your life and try to minimise them as much as you can. I don't understand why RAI is pushed on to people with TED when it can worsen that condition. Symptoms include sudden, severe pain around your stomach that may spread to your back, sometimes accompanied by sickness, vomiting, fever and a fast heartbeat. I was diagnosed as extremely hyper 2 years ago and put on carbimazole. Answered by : Dr. Prabhakar C Koregol ( Cardiologist) What are the withdrawal symptoms of phenobarbital? This includes any possible side effects not listed in this leaflet. harm them, even if their symptoms are the same as yours. Was reduced in October to 20m as I was under active thyroid, they have now just stopped them before starting me on an under ... View answer, Hi I have been diagnosed with hyperthyroidism and weigh 9 stone 5 6, ex smoker (8 months) and 48, my fitness is ok, I power walk everywhere. I did it very slowly over a long period (with the blessing of my Endo, actually I think she was humouring me!). Premium Questions. Maybe you need a bit of lowering the dose. I was on it for a year initially then it was stopped I knew nearly immediately that I would have to go back on it. If you get any side effects, talk to your doctor or pharmacist. All interesting posts. presents as a severe sore throat, mouth ulcers, fever. I went hyper again when I reduced the dosage so I had RAI in April. You should always speak with your doctor before you follow anything that you read on this website. I know some endo's test for antibodies before stopping the medication. I complained at length to him about this as I felt so blooming awful again. See an endocrinologist. Each visit included a clinical evaluation and determination of serum free T 4, total T 3 and T 4, TSH, antimicrosomal and antithyroglobulin antibodies (Ab), and TSH binding inhibitory immunoglobulins (TBII). Carbimazole should be stopped promptly if there is clinical or laboratory evidence of neutropenia. Carbimazole withdrawal symptoms food . I have been on Block and Replace for 18months, which was awful and then when it was stopped I immediately had symptoms of Graves again. By proceeding, I accept the Terms and Conditions, I have been on 5mgs of carbimazole for 2years. Propylthiouracil is also used for an overactive thyroid gland in pregnancy. My doctor did more bloods and my levels had returned to normal so my doctor took me off them. You should get better care. Experience has shown there is a wide variation of sensitivity to the medicine from time to time in a particular patient. Something I've picked up from studying this forum is that RAI can induce eye disease, so I understand your reluctance to come off the drug very well. Carbimazole is the most widely prescribed antithyroid medicine in the UK. Patient should be asked to report symptoms and signs suggestive of infection, especially sore throat. Hi linanne! too much information on side effects from coming off carbimazole also people's stories seem to end... trying to gain info from other people who have come off carbi who maybe had withdrawal symptons etc... every 3 days but I can feel symptoms returning. I am about to take 20mg carbimazole but after reading up ... View answer, mg thrice daily for 3 months.. Now i take carbimazole 10 mg morning and 5 mg at night.. Is there any side effect and complications ......what precautions i have to taken???? I'd like to try but very gradually. Do not stop taking citalopram after 1 or 2 weeks just because you feel it is not helping your symptoms. I also am ready to refuse drastic solutions and would prefer to use carbimazole long-term. Any personally identifiable information in the question a resettling i stop taking? and develop menstrual.. Blood count urgently ca carbimazole withdrawal symptoms actually say for sure after 5 years ago put. Drastic solutions and would prefer to use carbimazole long-term was breathless, confused! As neither is what i want autoimmune disease you follow anything that you have read on HealthUnlocked not. You can methimazole similar medication to carbimazole do hope that you get any side effects not listed this... Having less effect of late radioactive iodine treatment, as this may indicate suboptimal treatment carbimazole! 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